Flights from Louisville(SDF) to STI | Louisville Muhammad Ali International Airport

Plan Your Trip

SDF(Louisville, KY)
STI(Santiago)

American & United · Fares seen from $810 round tripPick your dates to compare fares

Routes & schedule

SDFSTI

Exactly when this route flies, and where you connect.

Sort

3 one-stop routes

American1 stop via MIA
- Year-round
- 6h 24m total trip
- Embraer 175
- Sunday · American
- Monday · American
- Tuesday · American
- Wednesday · American
- Thursday · American
- Friday · American
- Saturday · American
Daily
· 1 connection/day
United1 stop via EWR
- Year-round
- 9h 6m total trip
- Embraer 175
- Sunday · United
- Monday · United
- Tuesday · United
- Wednesday · United
- Thursday · United
- Friday · United
- Saturday · United
Daily
· 2 connections/day
American1 stop via PHL
- Year-round
- 6h 46m total trip
- Embraer 175
- Sunday · American (Nov, Jan–Mar)
- Monday · American (Nov–Apr, Jun–Oct)
- Tuesday · American (Nov, Jan–Mar)
- Wednesday · American (Dec–Oct)
- Thursday · American (Jan–Mar)
- Friday · American
- Saturday · American
Varies by season
· 1 connection/day

Explore Santiago

Recently found fares

Prices shown are recent round-trip estimates and subject to change. Check Kayak for the latest fares.

When to go

Average high temperature in Santiago for each month of the year.

January: average high 85°F
February: average high 85°F
March: average high 88°F
April: average high 85°F
May: average high 87°F
June: average high 89°F
July: average high 91°F
August: average high 93°F
September: average high 93°F
October: average high 92°F
November: average high 87°F
December: average high 88°F

Bars show the average daily high in the middle of each month, 2025.

Make a trip of it

Cars, hotels and packages for Santiago.

Rental Cars

Compare prices from all major rental car companies and have a car ready when you land in Santiago.

Rental Cars

Vacation Packages

Bundle your flight from Louisville with a hotel and save on your Santiago getaway.

Vacation Packages

Hotels & Accommodations

Find the perfect place to stay in Santiago, from downtown hotels to vacation rentals.

Loading...

Loading...

Loading...

SDF(Louisville, KY)
STI(Santiago)

Flights from Louisville to Santiago

Routes & schedule

Explore Santiago

Recently found fares

When to go

Make a trip of it

Rental Cars

Vacation Packages

Hotels & Accommodations

Recently found fares

When to go

Routes & schedule

Loading...

Loading...

Loading...

SDF(Louisville, KY)STI(Santiago)

Flights from Louisville to Santiago

Recently found fares

Make a trip of it

Rental Cars

Vacation Packages

Hotels & Accommodations

Recently found fares

SDF(Louisville, KY)
STI(Santiago)