Flights
Packages
Hotels
Destination Map
Destination List
Main Website

Loading...

11050 W. G. Rogell Dr
Building 602
Detroit, Michigan 48242

Cookie Policy Privacy Policy Terms & Conditions Unsubscribe Cookie Preferences

™ Trademarks of Airport One, LLC
©2026 AirportOne LLC - All rights reserved.

Cookie Policy

Terms & Conditions

Privacy Policy

Unsubscribe

Cookie Preferences

™ Trademarks of Airport One, LLC
©2026 AirportOne LLC - All rights reserved.

Flights
Packages
Hotels

Loading...

Search Flights

DTW(Detroit, Michigan)
TUP(Tupelo, MS)

Flights from Detroit to Tupelo

Pick your dates to compare fares

DTW

Detroit, Michigan

TUP

Tupelo, MS

Select dates

NonstopOne-stop

Include nearby dates in search

Select dates

NonstopOne-stop

Include nearby dates in search

DTWTUP

Vacation Packages

Vacation Packages

Discover unbeatable vacation deals from Tupelo or start planning your next getaway.

Vacation Packages

Hotels & Accommodations

Hotels & Accommodations

Find the perfect place to stay—near Tupelo or wherever your travels take you.

Hotels & Accommodations

Flights from Detroit(DTW) to TUP | Detroit Metropolitan Wayne County Airport

Local Weather in Tupelo

TODAYSep 25
81° / 65°
SatSep 26
83° / 63°