
Rental Cars
Compare prices from all major rental car companies and have a car ready when you land in Santo Domingo.
Rental Cars
Santo Domingo, the vibrant capital of the Dominican Republic, is a city where history and modern life blend effortlessly. Founded in 1496, it’s the oldest continuously inhabited European settlement in the Americas, and its Colonial Zone - now a UNESCO World Heritage Site - invites visitors to wander cobblestone streets lined with centuries-old cathedrals, plazas, and charming courtyards. The iconic Catedral Primada de América and Alcázar de Colón stand as timeless reminders of the city’s Spanish colonial heritage. Beyond its historic core, Santo Domingo pulses with Dominican rhythm and energy. The Malecón, a seaside boulevard, comes alive with music, restaurants, and ocean views, while the city’s art galleries, boutiques, and cafés showcase its modern creativity. Enjoy local flavors like mofongo or fresh seafood, and take in the warmth of Dominican hospitality. Whether exploring the past or embracing the city’s contemporary flair, Santo Domingo offers a colorful gateway to the soul of the Caribbean.
Cars, hotels and packages for Santo Domingo.

Compare prices from all major rental car companies and have a car ready when you land in Santo Domingo.
Rental Cars
Bundle your flight from Detroit with a hotel and save on your Santo Domingo getaway.
Vacation Packages
Find the perfect place to stay in Santo Domingo, from downtown hotels to vacation rentals.
Average high temperature in Santo Domingo for each month of the year.
November average high is 87°
Easily look up flight paths, departure frequencies, and timetables to plan your journey without the pressure of booking.
Map of 12 one-stop routes from Detroit (DTW) to Santo Domingo (SDQ): 1. American via Miami (MIA); 2. American via Philadelphia (PHL); 3. Delta via Atlanta (ATL); 4. Delta via New York City - JFK (JFK); 5. United via Newark (EWR); 6. JetBlue via Boston (BOS); 7. JetBlue via Fort Lauderdale (FLL); 8. JetBlue via New York City - JFK (JFK); 9. Frontier via Orlando (MCO); 10. United via Houston (IAH)
Prices shown are recent round-trip estimates and subject to change. Check Kayak for the latest fares.